We recently upgraded from 5.2.8.x to 22.214.171.124 and as of a sudden certain things did not work anymore. For example getting different JS with JSLoader.cfc didn't work anymore and other things related to the mapping called mapping-tag. Things that stopped working:
JSLoader.cfc was not found anymore
Caches are not found anymore
Database Drivers are not found anymore
I created a workaround by manually creating the mapping-tag manually and pointing it to the server-context/library/tag directory.